Figure 2A

Contact matrices show that loop domains in untreated HCT-116-RAD21-mAC cells (top) disappear after auxin treatment (bottom). Three representative loci are shown (at 10kb resolution): chr8:133.8-134.6Mb (left), chr4:40.8-42.1Mb (middle) and chr1:91.9-95.8Mb (right).


Untreated

Untreated